Dr. Susan K Seo

Dr. Susan Seo is a dual board-certified Infectious Disease and Internal Medicine specialist with over 31 years of experience at Memorial Sloan Kettering Cancer Center in New York City. A nationally recognized expert in infections among cancer and immunocompromised patients, she has authored more than 100 peer-reviewed publications with 500+ citations and led a Phase 3 clinical trial. She is currently accepting new patients.

Name: Dr. Susan Seo

Specialty: Infectious Disease (Internal Medicine)

Qualification / Board Certification: MD — University of North Carolina at Chapel Hill School of Medicine (Class of 1995) | American Board of Internal Medicine — Internal Medicine Certified | American Board of Internal Medicine — Infectious Disease Certified

Affiliation(s): Memorial Sloan Kettering Cancer Center — New York, NY

Location (City/State): New York, NY

Languages Spoken: English (additional languages not listed)

Accepting New Patients: Yes

NPI Number: Not publicly available

Accepting New Patients

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Description

Name: Dr. Susan Seo

Specialty: Infectious Disease (Internal Medicine)

Qualification / Board Certification: MD — University of North Carolina at Chapel Hill School of Medicine (Class of 1995) | American Board of Internal Medicine — Internal Medicine Certified | American Board of Internal Medicine — Infectious Disease Certified

Affiliation(s): Memorial Sloan Kettering Cancer Center — New York, NY

Location (City/State): New York, NY

Languages Spoken: English (additional languages not listed)

Accepting New Patients: Yes

NPI Number: Not publicly available

About the Doctor

Dr. Susan Seo is a dual board-certified Internal Medicine and Infectious Disease specialist with over 31 years of clinical experience, based in New York City. She earned her medical degree from the University of North Carolina at Chapel Hill School of Medicine in 1995, completed her residency in Internal Medicine at Beth Israel Deaconess Medical Center from 1995 to 1998, and went on to complete a highly specialized Fellowship in Infectious Disease at Memorial Sloan Kettering Cancer Center (MSK) from 1998 to 2000. Since then, she has remained at MSK — one of the world’s most prestigious cancer institutions — where she is one of only 33 infectious disease specialists on staff, serving a uniquely complex and immunocompromised patient population.

Dr. Seo is a nationally and internationally recognized expert in infectious disease management in cancer patients. She has authored and co-authored more than 100 publications with over 500 citations in the medical literature, contributing groundbreaking research in areas such as respiratory viral infections after CAR-T cell therapy, pneumococcal disease in cancer patients, antibiotic stewardship, and infection prevention following hematopoietic cell transplantation. She has also led a completed Phase 3 clinical trial investigating prophylactic strategies against streptococcal sepsis in transplant patients. Licensed in New York, New Jersey, and Florida, Dr. Seo brings a truly elite level of expertise to the intersection of oncology and infectious disease. She is currently accepting new patients.

Key Highlights:

  • 31+ years of experience in infectious disease and internal medicine
  • Dual board-certified in Internal Medicine and Infectious Disease
  • One of 33 infectious disease specialists at Memorial Sloan Kettering Cancer Center
  • 100+ publications and 500+ citations in peer-reviewed medical literature
  • Principal investigator on a completed Phase 3 clinical trial (NIH/ClinicalTrials.gov)
  • Expert in infections in immunocompromised and cancer patients
  • Licensed in New York, New Jersey, and Florida
  • Member of the American College of Physicians (ACP)
  • Currently accepting new patients

Education & Training

Medical School: University of North Carolina at Chapel Hill School of Medicine — Class of 1995

Residency: Beth Israel Deaconess Medical Center — Internal Medicine, 1995–1998

Fellowship / Additional Training: Memorial Sloan Kettering Cancer Center — Infectious Disease, 1998–2000

Medical Conditions Treated

Infectious Disease in Cancer & Immunocompromised Patients:

  • Bacterial Infections in Cancer Patients (Sepsis, Bacteremia)
  • Streptococcal & Pneumococcal Infections
  • Fungal Infections (Aspergillosis, Candidiasis, Cryptococcosis)
  • Viral Infections (RSV, Influenza, COVID-19, CMV, EBV)
  • Infections Following Hematopoietic Cell Transplantation (HCT)
  • Infections Following CAR-T Cell Therapy
  • Opportunistic Infections in Immunosuppressed Patients
  • Febrile Neutropenia Management
  • Healthcare-Associated & Hospital-Acquired Infections
  • Antibiotic-Resistant Bacterial Infections (MRSA, VRE, ESBL)

General Infectious Disease:

  • Community-Acquired Pneumonia
  • Urinary Tract Infections (UTIs) & Complicated UTIs
  • Skin & Soft Tissue Infections
  • Gastrointestinal Infections (C. difficile, enteric pathogens)
  • HIV & AIDS-Related Infections
  • Tuberculosis & Mycobacterial Infections
  • Sexually Transmitted Infections (STIs)
  • Travel Medicine & Tropical Infections
  • Tick-Borne Illnesses (Lyme Disease, Ehrlichiosis)
  • Respiratory Syncytial Virus (RSV) & Respiratory Viral Infections

Medical Procedures Performed

  • Comprehensive Infectious Disease Consultations
  • Fever & Infection Workup in Immunocompromised Patients
  • Blood Culture Interpretation & Bacteremia Management
  • Antimicrobial Therapy Selection & Optimization
  • Antibiotic Stewardship Program Participation
  • Prophylactic Infection Prevention Protocol Development
  • Fungal Infection Diagnosis & Antifungal Management
  • Viral Load Monitoring & Antiviral Therapy Management
  • Transplant Infection Surveillance & Management
  • CAR-T Cell Therapy Infection Risk Assessment
  • Isolation & Infection Control Protocol Implementation
  • Diagnostic Lab Work Interpretation (cultures, PCR, serology)
  • Clinical Trial Enrollment & Research Protocol Oversight
  • Vaccination Recommendations for Immunocompromised Patients
  • Multidisciplinary Team Consultations & Care Coordination

Services Offered

Dr. Seo’s practice at Memorial Sloan Kettering Cancer Center offers an exceptionally specialized range of infectious disease services, designed specifically for cancer patients and others with compromised immune systems. Her practice sits at the critical intersection of oncology and infectious disease — a highly complex clinical environment where the risks of infection are amplified by chemotherapy, radiation, transplantation, and advanced immunotherapy treatments.

Infectious Disease Consultation & Management in Cancer Patients:

Dr. Seo provides expert infectious disease consultations for patients undergoing active cancer treatment, including chemotherapy, stem cell transplantation, and CAR-T cell therapy. She evaluates and manages fever, unexplained infections, and sepsis in patients whose immune systems are severely weakened by their underlying disease or treatment — circumstances that demand a level of clinical precision and expertise found only at specialized cancer centers like MSK.

Transplant & Immunotherapy Infection Prevention:

A major area of Dr. Seo’s expertise is preventing and managing infections in patients undergoing hematopoietic cell transplantation (HCT) and CAR-T cell therapy. She has led clinical trials and published landmark research on prophylactic antibiotic strategies, respiratory viral infection outcomes post-CAR-T, and best practices for infection surveillance in transplant recipients. Her work directly informs national and international guidelines for transplant infectious disease management.

Antibiotic Stewardship & Antimicrobial Optimization:

Dr. Seo is actively involved in antibiotic stewardship — ensuring that antimicrobial medications are prescribed appropriately, effectively, and responsibly. Her recent research on large language models for antibiotic prescribing reflects her forward-thinking approach to integrating technology and evidence-based medicine to optimize patient outcomes and reduce antibiotic resistance.

Clinical Research & Vaccine Strategy in Cancer Patients:

Dr. Seo conducts prospective research on pneumococcal serotype distribution and vaccine effectiveness in cancer patients, contributing critical evidence that shapes vaccination policies for immunocompromised populations. Patients under her care benefit directly from her access to the latest clinical trial findings and her ability to incorporate cutting-edge research into personalized treatment plans.

Services at a Glance:

  • Infectious disease consultation for cancer and immunocompromised patients
  • Febrile neutropenia evaluation and management
  • Transplant and CAR-T cell therapy infection prevention and treatment
  • Fungal, bacterial, and viral infection diagnosis and management
  • Antibiotic stewardship and antimicrobial optimization
  • Prophylactic infection prevention protocol development
  • Respiratory viral infection management (RSV, influenza, COVID-19)
  • HIV and opportunistic infection management
  • Travel medicine and vaccination recommendations
  • Clinical trial participation and research-informed care
  • Multidisciplinary oncology team consultation and coordination
  • Hospital-acquired and antibiotic-resistant infection management

Accepted Insurances

Insurance information not publicly listed. Please contact Memorial Sloan Kettering Cancer Center directly to confirm accepted insurance plans:

  • Phone: +1 (507) 607-4371

Practice Locations

Location 1 Address: 530 East 74th Street, New York, NY 10021 Phone: +1 (507) 607-4371

Hospital Affiliations

  • Memorial Sloan Kettering Cancer Center — New York, NY (Primary Affiliation — Infectious Disease Specialist)
  • Beth Israel Deaconess Medical Center — Boston, MA (Residency Training Affiliation)

Clinical Trials

  • Trial of Prophylactic Versus Empirical Vancomycin for the Prevention of Streptococcal Sepsis After Hematopoietic Cell Transplantation — Phase 3, Completed (Enrollment began November 2003)

Awards, Honors & Recognition

  • CMS Meaningful Use Stage 1 Certification — Sunrise Ambulatory Care, Allscripts, 2016–2017
  • CMS Meaningful Use Stage 1 Certification — MyMSK, Memorial Sloan Kettering, 2016–2017

Publications & Research

PubMed: 100+ Publications | 500+ Citations

Recent Notable Publications:

  • Respiratory Syncytial Virus After Chimeric Antigen Receptor T-cell Therapy: Risk Factors and Outcomes in a Multicenter Retrospective Cohort — Clinical Infectious Diseases, April 2026
  • Comparing Large Language Models for Antibiotic Prescribing: An Updated Analysis Using the Same Clinical Benchmark — Clinical Microbiology and Infection, April 2026
  • Pneumococcal Serotype Distribution and Outcomes in Cancer Patients with Community-Acquired Pneumonia: A Prospective Study Using the 15-Valent Pneumococcal Conjugate Vaccine — International Journal of Infectious Diseases, March 2026

Professional Memberships

  • American College of Physicians (ACP) — Member
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