Dr. Mustaqeem A. Siddiqui
Dr. Mustaqeem A. Siddiqui is a fellowship-trained oncologist and hematologist with over 20 years of experience, practicing at Mayo Clinic in Rochester, Minnesota β one of the world’s foremost cancer treatment centers. He earned his medical degree from Aga Khan Medical College and completed both his Internal Medicine Residency and his Hematology and Medical Oncology Fellowship at Mayo Clinic College of Medicine and Science. Dr. Siddiqui specializes in hematological malignancies, solid tumor oncology, and chronic anemia management, with access to Mayo Clinic’s full range of advanced diagnostics, multidisciplinary care teams, and clinical trials. Mayo Clinic is ranked #4 nationally in Cancer care and holds High Performing designations across multiple cancer categories. He accepts Aetna, Blue Cross Blue Shield, Elevance, and United Healthcare including Medicare, and is currently welcoming new patients. His NPI number is 1669480133.
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Name: Dr. Mustaqeem A. Siddiqui
Specialty: Oncology (General Oncology)
Qualification/Board Certification: Aga Khan Medical College; Fellowship in Hematology and Medical Oncology β Mayo Clinic College of Medicine and Science; State Medical License (Active through 2026); CA State Medical License (Active through 2027)
Affiliation(s): Mayo Clinic
Locations (City/State): Rochester, Minnesota
Languages Spoken: English
Accepting New Patients: Yes
NPI Number: 1669480133
About the Doctor
Dr. Mustaqeem A. Siddiqui is a distinguished and fellowship-trained oncologist and hematologist based in Rochester, Minnesota, with over 20 years of experience in the diagnosis and treatment of cancers and blood disorders. He earned his medical degree from Aga Khan Medical College, one of Pakistan’s most prestigious and internationally recognized medical institutions known for producing exceptionally trained physicians who serve patients worldwide. He then completed his Internal Medicine Residency at Mayo Clinic College of Medicine and Science (2004β2007) and his Fellowship in Hematology and Medical Oncology at Mayo Clinic College of Medicine and Science (2007β2011) β completing his entire post-graduate training at one of the world’s most renowned medical institutions.
Dr. Siddiqui currently practices at Mayo Clinic in Rochester, Minnesota, the flagship campus of the globally recognized Mayo Clinic health system. His affiliation with Mayo Clinic places him at one of the most elite cancer care institutions in the world β ranked #4 nationally in Cancer care and appearing on the Best Hospitals Honor Roll, with high performance designations in colon cancer surgery, gynecological cancer surgery, leukemia, lymphoma and myeloma, lung cancer surgery, and prostate cancer surgery. This exceptional institutional setting provides Dr. Siddiqui’s patients with access to the most advanced cancer diagnostics, multidisciplinary tumor boards, cutting-edge clinical trials, and world-class subspecialist collaboration available anywhere in the country. He has demonstrated above-average treatment volumes in chronic anemia compared to the Minnesota state average, reflecting his deep clinical expertise in hematological conditions that commonly intersect with oncological disease. He accepts Aetna, Blue Cross Blue Shield, Elevance, and United Healthcare, including Medicare, and is currently welcoming new patients.
Highlights at a glance:
- Over 20 years of experience in oncology and hematology
- Entire post-graduate training completed at Mayo Clinic β one of the world’s top medical institutions
- Fellowship in Hematology and Medical Oncology β Mayo Clinic College of Medicine and Science
- Affiliated with Mayo Clinic β ranked #4 nationally in Cancer care and on the Best Hospitals Honor Roll
- Mayo Clinic holds High Performing designations in leukemia, lymphoma and myeloma, lung cancer surgery, colon cancer surgery, gynecological cancer surgery, and prostate cancer surgery
- Above-average treatment volumes in chronic anemia in Minnesota
- Medical degree from Aga Khan Medical College β one of Pakistan’s most internationally respected medical institutions
- Dual state licensure in Minnesota and California
- Accepts Medicare and multiple major commercial insurance plans
- Active Minnesota State Medical License through 2026
- Currently accepting new patients
Education & Training
- Medical School: Aga Khan Medical College
- Residency: Internal Medicine β Mayo Clinic College of Medicine and Science, Rochester (2004β2007)
- Fellowship: Hematology and Medical Oncology β Mayo Clinic College of Medicine and Science, Rochester (2007β2011)
- Subspecialty Focus: General Oncology with expertise in hematological malignancies, medical oncology, and chronic anemia management
Medical Conditions Treated
- Leukemia (acute and chronic β AML, ALL, CML, CLL)
- Lymphoma (Hodgkin’s and Non-Hodgkin’s)
- Multiple myeloma and plasma cell disorders
- Chronic anemia and hematological disorders
- Myelodysplastic syndromes (MDS)
- Myeloproliferative neoplasms (MPN)
- Lung cancer (non-small cell and small cell)
- Colon and colorectal cancer
- Prostate cancer
- Gynecological cancers (ovarian, cervical, uterine)
- Breast cancer
- Gastrointestinal cancers (gastric, pancreatic, hepatocellular)
- Kidney and bladder cancers
- Head and neck cancers
- Thyroid and endocrine cancers
- Solid tumor malignancies of various organ systems
- Paraneoplastic syndromes and cancer-related complications
- Thrombocytopenia, neutropenia, and cytopenias
Medical Procedures Performed
- Comprehensive oncological evaluations and cancer staging assessments
- Bone marrow biopsy and aspiration
- Chemotherapy administration and regimen management
- Targeted therapy and precision oncology treatment planning
- Immunotherapy and checkpoint inhibitor management
- Hormone therapy for hormone-sensitive cancers
- Hematological disorder evaluation and management
- Tumor marker monitoring and cancer surveillance
- PET scan, CT scan, and MRI interpretation for staging and response assessment
- Blood transfusion and transfusion medicine coordination
- Clinical trial enrollment and investigational therapy management
- Stem cell transplant evaluation and referral coordination
- Palliative oncology consultations
- Multidisciplinary tumor board case presentation and coordination
- Port placement and central venous access coordination
- Cancer genetic counseling referral and BRCA/hereditary cancer evaluation
Services Offered
Dr. Siddiqui provides a comprehensive and world-class range of oncological and hematological services at Mayo Clinic in Rochester, one of the most advanced and highly ranked cancer treatment centers in the world. His practice combines deep subspecialty expertise in both hematological malignancies and solid tumor oncology with access to Mayo Clinic’s extraordinary resources β including cutting-edge diagnostic technologies, a robust clinical trials program, and seamless multidisciplinary collaboration with surgical oncologists, radiation oncologists, radiologists, pathologists, and supportive care specialists.
Hematological Malignancy Care:
Dr. Siddiqui has particular expertise in the management of blood cancers including leukemia, lymphoma, multiple myeloma, and myelodysplastic syndromes β conditions for which Mayo Clinic holds national High Performing designations. He provides comprehensive evaluation, accurate staging, and individualized treatment planning using the latest chemotherapy regimens, targeted therapies, and immunotherapy approaches, coordinating bone marrow transplant evaluations and stem cell transplant referrals when indicated.
Medical Oncology for Solid Tumors:
Dr. Siddiqui evaluates and manages a broad range of solid tumor cancers including lung, colon, prostate, gynecological, breast, and gastrointestinal malignancies, developing evidence-based treatment plans that leverage Mayo Clinic’s multidisciplinary tumor board process and access to the most current standard-of-care and investigational therapies.
Precision & Targeted Oncology:
At Mayo Clinic, Dr. Siddiqui has access to advanced genomic and molecular profiling of tumors, enabling him to identify actionable genetic mutations and prescribe targeted therapies that offer greater efficacy and reduced toxicity compared to conventional chemotherapy for eligible patients.
Chronic Anemia & Hematological Disorders:
With above-average treatment volumes in chronic anemia in Minnesota, Dr. Siddiqui provides expert evaluation and management of anemia and related hematological conditions β including those arising as complications of cancer, cancer treatment, or primary blood disorders β using evidence-based approaches to restore red blood cell health and patient vitality.
Clinical Trials & Investigational Therapy:
Practicing at Mayo Clinic provides Dr. Siddiqui’s patients with access to one of the nation’s most active and diverse oncology clinical trials programs, offering opportunities to participate in cutting-edge investigational treatments that may not yet be available outside major academic cancer centers.
Palliative & Supportive Oncology:
Dr. Siddiqui integrates palliative care principles into his oncology practice, ensuring that patients’ quality of life, symptom burden, and emotional well-being are carefully addressed alongside active cancer treatment, in close coordination with Mayo Clinic’s dedicated palliative care and supportive oncology teams.
Services at a glance:
- Comprehensive cancer evaluations and staging
- Leukemia, lymphoma, and multiple myeloma management
- Myelodysplastic syndrome and myeloproliferative neoplasm care
- Solid tumor oncology (lung, colon, prostate, gynecological, breast, GI)
- Chemotherapy administration and regimen management
- Targeted therapy and precision oncology treatment
- Immunotherapy and checkpoint inhibitor management
- Hormone therapy for hormone-sensitive cancers
- Bone marrow biopsy and hematological evaluation
- Chronic anemia and cytopenias management
- Stem cell transplant evaluation and referral coordination
- Clinical trial enrollment and investigational therapy access
- Tumor genetic and molecular profiling
- Cancer surveillance and remission monitoring
- Palliative and supportive oncology care
- Multidisciplinary tumor board case coordination
Accepted Insurances
- Aetna β EPO, HMO, Medicare, POS, PPO
- Blue Cross Blue Shield of Massachusetts β Medicare, PPO
- Elevance (formerly Anthem) β EPO, HMO, Medicare, POS, PPO
- United Healthcare β Medicare, PPO
Please contact the practice directly to confirm your specific plan is accepted before scheduling an appointment.
Practice Locations
Location 1 Address: 200 1st St SW, Rochester, MN 55905 Phone: (507) 284-2511
Hospital Affiliations
- Mayo Clinic β Rochester, MN (Best Hospitals Honor Roll; Ranked #4 in Cancer; High Performing in Colon Cancer Surgery, Gynecological Cancer Surgery, Leukemia/Lymphoma & Myeloma, Lung Cancer Surgery, and Prostate Cancer Surgery)
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